News

15.09.2017 - New review article on the role of IP3R-Mediated Ca2+ Release in Migration and Invasion.

Ritaine A, Shapovalov G, Prevarskaya N.
Metabolic Disorders and Cancer: Store-Operated Ca2+ Entry in Cancer: Focus on IP3R-Mediated Ca2+ Release from Intracellular Stores and Its Role in Migration and Invasion.
Adv Exp Med Biol. 2017;993:623-637. doi: 10.1007/978-3-319-57732-6_31.
PubMed

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15.07.2017 - New review article on the role of TRP channels and calcium in cell death and survival.

Fliniaux I, Germain E, Farfariello V, Prevarskaya N.
TRPs and Ca2+ in cell death and survival.
Cell Calcium. 2017 Jul 15. pii: S0143-4160(17)30081-7. doi: 10.1016/j.ceca.2017.07.002.
PubMed

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31.05.2017 - New publication showing that a TRPM8 inhibits endothelial cell migration via a non-channel function by trapping the small GTPase Rap1.

Genova T, Grolez GP, Camillo C, Bernardini M, Bokhobza A, Richard E, Scianna M, Lemonnier L, Valdembri D, Munaron L, Philips MR, Mattot V, Serini G, Prevarskaya N, Gkika D, Pla AF.
TRPM8 inhibits endothelial cell migration via a non-channel function by trapping the small GTPase Rap1.
J Cell Biol. 2017 Jul 3;216(7):2107-2130. doi: 10.1083/jcb.201506024. Epub 2017 May 26.
PubMed

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10.04.2017 - New review article on calcium signalling in cancer.

Monteith GR, Prevarskaya N, Roberts-Thomson SJ.
The calcium-cancer signalling nexus.
Nat Rev Cancer. 2017 Apr 7. doi: 10.1038/nrc.2017.18.
PubMed

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22.03.2017 - New review article on molecular mechanisms of tumor invasion.

Iamshanova O, Fiorio Pla A, Prevarskaya N.
Molecular mechanisms of tumor invasion: regulation by calcium signals.
J Physiol. 2017 Mar 17. doi: 10.1113/JP272844.
PubMed

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14.03.2017 - New publication on TRPA1 in prostate cancer associated fibroblasts.

Vancauwenberghe E, Noyer L, Derouiche S, Lemonnier L, Gosset P, Sadofsky LR, Mariot P, Warnier M, Bokhobza A, Slomianny C, Mauroy B, Bonnal JL, Dewailly E, Delcourt P, Allart L, Prevarskaya N, Roudbaraki M.
Activation of mutated TRPA1 ion channel by resveratrol in human prostate cancer associated fibroblasts (CAF).
Mol Carcinog. 2017 Mar 9. doi: 10.1002/mc.22642.
PubMed

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11.02.2017 - International Day of Women and Girls in Science. Read more... 

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17.01.2017 - New publication showing that TRPA1 could mediate the effects of environmental factors on tumor microenvironment interactions and prostate cancer progression. 

Derouiche S, Mariot P, Warnier M, Vancauwenberghe E, Bidaux G, Gosset P, Mauroy B, Bonnal JL, Slomianny C, Delcourt P, Dewailly E, Prevarskaya N, Roudbaraki M.
Activation of TRPA1 Channel by Antibacterial Agent Triclosan Induces VEGF Secretion in Human Prostate Cancer Stromal Cells.
Cancer Prev Res (Phila). 2017 Mar;10(3):177-187.
PubMed

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21.11.2016 - First Test Phycell Chess Championship. Congratulations to Pascal and Mirto! Pascal won the first prize and Mirto won the secon prize of the First Test Phycell Chess Championship.

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22.09.2016 - New publication on sodium imaging in prostate cancer cell lines.

Iamshanova O, Mariot P, Lehen'kyi V, Prevarskaya N.
Comparison of fluorescence probes for intracellular sodium imaging in prostate cancer cell lines.
Eur Biophys J. 2016 Oct;45(7):765-777.
PubMed